Sibutramine Hydrochloride (BTS 54-524) is discontinued (DEA controlled substance). Sibutramine hydrochloride monohydrate is a novel 5-HT (serotonin) and noradrenaline reuptake inhibitor (SNRI). The IC50 for Sibutramine block of voltage-gated K+ channel (KV)4.3 is 17.3 μM. It is a 5-HT and noradrenalin re-uptake inhibitor. It produces weight loss in rats via inhibition of food intake and increased energy expenditure. It exhibits anorectic properties, which induces increased energy expenditure and weight loss.

纯度：≥98%

CAS：84485-00-7