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LM985
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LM985图片
CAS NO:87626-56-0
规格:98%
分子量:379.45
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
LM985是一种带有黄酮环结构的化合物,具有抗肿瘤功效。
CAS:87626-56-0
分子式:C23H25NO4
分子量:379.45
纯度:98%
存储:Store at -20°C

Background:

LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities.


LM985 shows inhibitory effects against MAC 13 cells, but MAC 15A cells are less sensitive to LM985[1].


LM985 (200 mg/kg, s.c.) shows moderate activity against MAC 13, and after repeated injection 7 days, responses are considerably enhanced[2].


[1]. M. C. Bibby, et al. Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid). Br J Cancer. 1987 Feb; 55(2): 159-163. [2]. J. A. Double, et al. Pharmacokinetics and anti-tumour activity of LM985 in mice bearing transplantable adenocarcinomas of the colon. Br J Cancer. 1986 Oct; 54(4): 595-600.