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Rocastine(AHR-11325)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rocastine(AHR-11325)图片
CAS NO:91833-49-7
规格:98%
分子量:265.37
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Rocastine是一种选择性的,非镇静的H1拮抗剂,为抗组胺剂。
CAS:91833-49-7
分子式:C13H19N3OS
分子量:265.37
纯度:98%
存储:Store at -20°C

Background:

Rocastine is a selective, nonsedating H1 antagonist, acting as an antihistamine.



Rocastine is effective with a 15 min pretreatment time (PD50 = 0.13 mg/kg) as it is with a 1 hr pretreatment time (PD50 = 0.12 mg/kg). Rocastine protects guinea pigs from collapse induced by aerosolized antigen; rocastine is approximately 36x more potent than diphenhydramine and as potent as oxatomide and terfenadine. Rocastine does not alter the EEG of cats at doses in vast excess (150x) of its antihistaminic dose nor does it potentiate yohimbine toxicity in mice[1].


[1]. Nolan JC, et al. Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine. Agents Actions. 1989 Aug;28(1-2):53-61.