Clindamycin sulfoxide is an active metabolite of the antibiotic clindamycin.
CAS:22431-46-5
分子式:C18H33ClN2O6S
分子量:441
纯度:98%
存储:Store at -20°C
Background:
Clindamycin sulfoxide is an active metabolite of the antibiotic clindamycin . It is formed via S-oxidation of clindamycin primarily by the cytochrome P450 (CYP) isoform CYP3A4. Clindamycin sulfoxide inhibits the growth of P. prevotti, B. fragilis, and C. sordelli in vitro with MIC values of 2, 2, and 1 mg/L, respectively.