Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor.
CAS:1644545-52-7
分子式:C14H13ClF6N6
分子量:414.74
纯度:98%
存储:Store at -20°C
Background:
Vorasidenib (AG-881) is an orally available, brain penetrant second-generation dual mutant isocitrate dehydrogenases 1 and 2 (mIDH1/2) inhibitor. Vorasidenib (AG-881) exhibits nanomolar inhibition of (D)-2-hydroxyglutarate (D-2-HG), and the IC50 ranges of 0.04