diacetoxy Scirpenol (DAS) is a potent, trichothecene mycotoxin produced by certain Fusarium strains, which play an important role as plant pathogens, causing a wide range of diseases.
CAS：2270-40-8
分子式：C19H26O7
分子量：366.4
纯度：98%
存储：Store at -20°C

Background:

diacetoxy Scirpenol (DAS) is a potent, trichothecene mycotoxin produced by certain Fusarium strains, which play an important role as plant pathogens, causing a wide range of diseases. It is toxic to fungi, plants, animals, and various mammalian cell cultures, inhibiting de novo protein synthesis. In a biological activity assay, DAS was shown to inhibit expression of the Arabidopsis MAMP-responsive reporter gene WRKY29p::GUS with an IC50 value of 50 nM, thereby suppressing a rapid cell death immune response important for plant defense.