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Curculigoside
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Curculigoside图片
CAS NO:85643-19-2
包装:20mg
规格:98%
市场价:1786元
分子量:466.44

产品介绍
Extracted?from?Curculigo glabrescens (Ridl.) Merr.;Store?the?product?in?sealed,?cool?and?dry?condition
CAS:85643-19-2
分子式:C22H26O11
分子量:466.44
纯度:98%
存储:Store at -20°C

Background:

Curculigoside is the main saponin in C. orchioide, exerts significant antioxidant, anti-osteoporosis, antidepressant and neuroprotection effects. Curculigoside possesses significant anti-arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF-κB signaling pathway[1].


Curculigoside (1-64 μg/ml; 72 hours) exerts significant inhibitory effects on MH7A cell viability between 1 and 64 μg/ml in MH7A cells[1].Curculigoside (4-16 μg/ml; 24 hours) decreases the protein expression of JAK1, JAK3 and STAT3 compared to the TNF-α group[1].


参考文献:
[1]. Tan S, et al. Curculigoside exerts significant anti arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF κB signaling pathway. Mol Med Rep. 2019 Mar;19(3):2057-2064.