Merodantoin is an apoptosis inducer, triggering ROS dependent autophagy-associated apoptosis in a variety of human cancer cell lines and against mutant KRAS expressing cancer cells involving AKT-dependent ROS production. References: Iskandar K, Rezlan M, Yadav SK, Foo CH, Sethi G, Qiang Y, Bellot GL, Pervaiz S. Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS Production. Antioxid Redox Signal. 2016 May 10;24(14):781-94. doi: 10.1089/ars.2015.6362. Epub 2016 Feb 26. PubMed PMID: 26714745.
纯度:≥98%
CAS:143413-73-4