您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Taurolithocholic Acid(sodium salt)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Taurolithocholic Acid(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Taurolithocholic Acid(sodium salt)图片
CAS NO:6042-32-6
规格:98%
分子量:505.7
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
Taurolithocholic acid (TLCA) is a taurine-conjugated form of the secondary bile acid lithocholic acid.
CAS:6042-32-6
分子式:C26H44NO5S.Na
分子量:505.7
纯度:98%
存储:Store at -20°C

Background:

Taurolithocholic acid (TLCA) is a taurine-conjugated form of the secondary bile acid lithocholic acid . TLCA (75 μM) increases caspase-3 and -7 activity in Hep3B cells transfected with sodium taurocholate cotransporting peptide (NTCP), but not nontransfected Hep3B cells. It has been used to induce cholestasis in ex vivo and in vivo animal models of hepatocellular cholestasis. Serum levels of TLCA increase approximately 5-fold in within two hours during an oral lipid tolerance test in humans.