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p,p'-DDE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
p,p'-DDE图片
CAS NO:72-55-9
规格:98%
分子量:318
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
p,p'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT.
CAS:72-55-9
分子式:C14H8Cl4
分子量:318
纯度:98%
存储:Store at -20°C

Background:

p,p’-DDE is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass as well as sediment in the Huntsville Spring Branch-Indian Creek tributary system surrounding a DDT manufacturing plant where it is considered a persistent organic pollutant (POP). p,p’-DDE inhibits estrogen binding to rainbow trout estrogen receptors (rtERs) with an IC50 value of 8 µM. It induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles. p,p’-DDE (50-100 µM) also decreases ATP levels, the proportion of sperm with high mitochondrial membrane potential, and motility of human sperm in vitro.