competitive inhibitor of the enzyme alcohol dehydrogenase
CAS:7554-65-6
分子式:C4H6N2
分子量:82.1
纯度:98%
存储:Store at -20°C
Background:
Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase which plays a key role in the metabolism of ethylene glycol and methanol.
参考文献:
[1]. Casavant MJ. Fomepizole in the treatment of poisoning. Pediatrics. 2001 Jan;107(1):170.
[2]. Lepik KJ, et al. Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole. Ann Emerg Med. 2009 Apr;53(4):439-450.e10.