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Minodronic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Minodronic acid图片
CAS NO:180064-38-4
规格:98%
分子量:322.15
包装与价格:
包装价格(元)
200mg电议
500mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Minodronic acid (YM-529) 是第三代二磷酸盐,直接或间接地阻止增殖,诱导细胞凋亡,并抑制各种类型的癌细胞的转移。Minodronic acid (YM-529) 是一种参与疼痛的嘌呤 P2X2/3 受体拮抗剂。
CAS:180064-38-4
分子式:C9H12N2O7P2
分子量:322.15
纯度:98%
存储:Store at -20°C

Background:

Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain[1][2]. P2X2/3[2]




[1]. Sato K, et al. A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo. Br J Cancer. 2006 Nov 20;95(10):1354-61. [2]. Tanaka M, et al. Minodronic acid induces morphological changes in osteoclasts at bone resorption sites and reaches a level required for antagonism of purinergic P2X2/3 receptors. J Bone Miner Metab. 2018 Jan;36(1):54-63.