7-?Hydroxy-?3,?4-?dihydro-?2(1H)?-?quinolinone (3,4-Dihydro-7-hydroxy-2(1H)-quinolinone) 是一种弱 MAO-A 抑制剂,IC50 值为 183 μM,对 MAO-B 无作用。
CAS:22246-18-0
分子式:C9H9NO2
分子量:163.17
纯度:98%
存储:Store at -20°C
Background:
7-?Hydroxy-?3,?4-?dihydro-?2(1H)?-?quinolinone (3,4-Dihydro-7-hydroxy-2(1H)-quinolinone) is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].
IC50: 183 μM (MAO-A)[1]
7-?Hydroxy-?3,?4-?dihydro-?2(1H)?-?quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].
[1]. Meiring L, et al. Inhibition of monoamine oxidase by 3,4-dihydro-2(1H)-quinolinone derivatives. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5498-502.