MF-094是有效,选择性的USP30抑制剂,IC50为120nM。
CAS:2241025-68-1
分子式:C30H37N3O4S
分子量:535.7
纯度:98%
存储:Store at -20°C
Background:
MF-094 is a potent and selective USP30 inhibitor with an IC50 of 120 nM.
IC50: 120 nM (USP30)[1]
[1]. Kluge AF, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2655-2659.