N-Benzoyl-(2R,3S)-3-phenylisoserine是紫杉醇C-13的侧链,对紫杉醇较强的抗肿瘤活性至关重要。
CAS:132201-33-3
分子式:C16H15NO4
分子量:285.29
纯度:98%
存储:Store at -20°C
Background:
N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain and crucial for the strong antitumor activity of Taxol[1].
[1]. Iwao Ojima, et al. Efficient and Practical Asymmetric Synthesis of the Taxol C-13 Side Chain, N-Benzoyl-(2R,3S)-3-phenylisoserinea,n d Its Analogues via Chiral3-Hydroxy-4-aryl-&lactams through Chiral Ester Enolate-Imine Cyclocondensation.