The PtdIn phosphates play an important role in the generation and transduction of intracellular signals.
CAS:1415684-80-8
分子式:C35H61N3O24P4S.4Na
分子量:1155.8
纯度:98%
存储:Store at -20°C
Background:
The PtdIn phosphates play an important role in the generation and transduction of intracellular signals. PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.