Fulvestrant R enantiomer 是 Fulvestrant 的 R 型对映异构体。Fulvestrant 是一种可用于治疗乳腺癌的选择性雌激素受体 (ER) 拮抗剂。
CAS:1807900-80-6
分子式:C32H47F5O3S
分子量:606.77
纯度:98%
存储:Store at -20°C
Background:
Fulvestrant R enantiomer is the R enantiomer of Fulvestrant. Fulvestrant is a selective estrogen receptor (ER) antagonist which can be used to treat breast cancer.
[1]. Caprioglio D, et al. An alternative synthesis of the breast cancer drug fulvestrant (Faslodex•): catalyst control over C-C bond formation. Chem Commun (Camb). 2015 Oct 14;51(80):14866-8.
[2]. Osborne CK, et al. Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. Br J Cancer. 2004 Mar;90 Suppl 1:S2-6.