DMT1 blocker 1 是二价金属转运蛋白1 (DMT1) 的阻断剂，IC50 为0.64 μM，可以阻断体内肠细胞的铁摄取。
CAS：1354790-56-9
分子式：C16H14N4O2
分子量：294.31
纯度：98%
存储：Store at -20°C

Background:

DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo[1]. IC50: 0.64 μM (DMT1 blocker 1)[1]

[1]. Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5.