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Leucylarginylproline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Leucylarginylproline图片
CAS NO:133943-59-6
规格:98%
分子量:384.47
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Leucylarginylproline是血管紧张素转换酶(ACE)抑制剂,IC50值为0.27μM。
CAS:133943-59-6
分子式:C17H32N6O4
分子量:384.47
纯度:98%
存储:Store at -20°C

Background:

Leucylarginylproline is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 0.27μM.


Intravenous injection of Leucylarginylproline (30mg/kg) causes a decrease in the blood pressure. The maximum mean blood pressure reduction (about 15 mmHg) occurrs about 2 min after the injection[1]. Leucylarginylproline peptide reduces the blood pressure by about 15 mmHg at the fourth hour and shows a maximal reduction effect of about 35 mmHg at the eighth hour after oral administration[2].



[1]. Miyoshi S, et al. Structures and activity of angiotensin-converting enzyme inhibitors in an alpha-zein hydrolysate. Agric Biol Chem. 1991 May;55(5):1313-8. [2]. Chen TL, et al. Microencapsulation and modification of synthetic peptides of food proteins reduces the blood pressure of spontaneously hypertensive rats. J Agric Food Chem. 2003 Mar 12;51(6):1671-5.