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NO-Losartan A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NO-Losartan A图片
CAS NO:791122-48-0
规格:98%
分子量:602
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议

产品介绍
Angiotensin II is a hormone that plays an important role in regulating blood pressure.
CAS:791122-48-0
分子式:C30H28ClN7O5
分子量:602
纯度:98%
存储:Store at -20°C

Background:

Angiotensin II is a hormone that plays an important role in regulating blood pressure. Elevated levels of angiotensin II are implicated in inducing and maintaining hypertension, and also in the development of atherosclerosis. Both of these effects are mediated by the angiotensin II type 1 (AT1) receptor. Losartan is a mammalian AT1 receptor antagonist with a Ki value of 5-20 nM. In humans, losartan effectively controls hypertension while protecting renal function. Nitric oxide (NO) causes vasodilation and also inhibits platelet and neutrophil aggregation in the endothelium. NO-losartan A possesses similar anti-hypertensive effects to losartan, with the addition of the vasodilating effects of NO release.