6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions.
CAS：62770-50-7
分子式：C20H34O5
分子量：354.5
纯度：98%
存储：Store at -20°C

Background:

6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 µM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.