TRPM8 antagonist WS-3 是 TRPM8 的激动剂,其 EC50 值为 3.7 μM。
CAS:39711-79-0
分子式:C13H25NO
分子量:211.34
纯度:98%
存储:Store at -20°C
Background:
TRPM8 antagonist WS-3 is an agonist of TRPM8 with an EC50 of 3.7 μM.
EC50: 3.7 μM (TRPM8)[1]
[1]. Behrendt HJ, et al. Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol. 2004 Feb;141(4):737-45.