Palbinone是从芍药中提取的萜类物质,有效抑制3α羟基类固醇脱氢酶(3α-HSD)的活性,IC50值为46nM。具有抗炎功效。
CAS:139954-00-0
分子式:C22H30O4
分子量:358.47
纯度:98%
存储:Store at -20°C
Background:
Palbinone is a terpenoid isolated from the roots of Paeonia albiflora Pallas, potently inhibits 3α-hydroxysteroid dehydrogenase (3α-HSD), with an IC50 of 46 nM. Anti-inflammatory activity[1].
IC50: 46 nM (3α-HSD)[1]
[1]. Kadota S, et al. Palbinone, a novel terpenoid from Paeonia albiflora; potent inhibitory activity on 3 alpha-hydroxysteroid dehydrogenase. Chem Pharm Bull (Tokyo). 1993 Mar;41(3):487-90.