8-Hydroxyguanosine是氧化应激的系统标记,也可用作氢氧自由基对RNA损伤的标记。
CAS:3868-31-3
分子式:C10H13N5O6
分子量:299.24
纯度:98%
存储:Store at -20°C
Background:
8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA.
[1]. Fiala ES, et al. Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res. 1989 Oct 15;49(20):5518-22. [2]. Abe T, et al. Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer’s disease. J Neurosci Res. 2002 Nov 1;70(3):447-50.