BMH-7 is a p53 activator with potent antitumor activity. It regulates the p53 signaling pathway in bladder cancer cells. BMH-7 also induces apoptosis, changes cell size, and leads to cell death. BMH-7 is derived from quinazolinone, a small molecule that is able to activate the p53 tumor suppressor pathway. References: Zhang GH, Yuan JM, Qian G, Gu CX, Wei K, Mo DL, Qin JK, Peng Y, Zhou ZP, Pan CX, Su GF. Phthalazino[1,2-b]quinazolinones as p53 Activators: Cell Cycle Arrest, Apoptotic Response and Bak-Bcl-xl Complex Reorganization in Bladder Cancer Cells. J Med Chem. 2017 Aug 15. doi: 10.1021/acs.jmedchem.6b01769. [Epub ahead of print] PubMed PMID: 28745887.

纯度：≥98%

CAS：379247-14-0