Ethyl orsellinate is a lichen metabolite and a derivative of lecanoric acid that has antiproliferative activities.
CAS:2524-37-0
分子式:C10H12O4
分子量:196.2
纯度:98%
存储:Store at -20°C
Background:
Ethyl orsellinate is a lichen metabolite and a derivative of lecanoric acid that has antiproliferative activities. It inhibits the proliferation of human Hep-2 larynx carcinoma, MCF-7 breast cancer, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s = 31.2, 70.3, 47.5, 64.8, and 28.1 µg/ml, respectively). Ethyl orsellinate is toxic to brine shrimp (A. salina) with an LC50 value of 495 µM.