DC661
A potent PPT1 inhibitor
CAS：1872387-43-3
分子式：C??H??Cl?N?
分子量：552.58
纯度：98%
存储：Store at -20°C
Background:
DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor, inhibits autophagy, and acts as an anti-lysosomal agent. Anti-cancer activity[1].
DC661 (0.1 and 10 μM) accumulates autophagic vesicles in melanoma cells[1].
Reference:
[1]. Rebecca VW, et al. PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer. ancer Discov. 2019 Feb;9(2):220-229.
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