3,5-Diiodothyropropionic acid (DITPA) is an inotropic thyroid hormone analogue of L-thyroxine that binds to the thyroid hormone receptors TRα and TRβ (Kas = 2.4 and 4.06 x 107 M-1, respectively, for human recombinant receptors).
CAS:1158-10-7
分子式:C15H12I2O4
分子量:510.1
纯度:98%
存储:Store at -20°C
Background:
3,5-Diiodothyropropionic acid (DITPA) is an inotropic thyroid hormone analogue of L-thyroxine that binds to the thyroid hormone receptors TRα and TRβ (Kas = 2.4 and 4.06 x 107 M-1, respectively, for human recombinant receptors).1 DITPA increases mRNA expression of α-myosin heavy chain (α-MHC) in primary rat cardiomyocytes (EC50 =