Mildronate dihydrate (Meldonium) is a potent inhibitor of biosynthesis of
L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a
competitive inhibitor of renal carnitine reabsorption. Mildronate (40
μM) inhibits the reaction of γ-butyrobetaine hydroxylase with
γ-butyrobetaine with Km and Vmax of 36.8 μM and 0.08 nmol/min/mg
protein, respectively.
纯度:≥98%
CAS:86426-17-7