IACS-8968(R-enantiomer)是IACS-8968的R型对映异构体。IACS-8968是IDO和TDO的双抑制剂,其pIC50s值分别为6.43,<5。
CAS:2239305-67-8
分子式:C17H18F3N5O2
分子量:381.35
纯度:98%
存储:Store at -20°C
Background:
IACS-8968 (R-enantiomer) is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and<5 for TDO, respectively.
IDO, TDO[1].
[1]. ARYL SULFONOHYDRAZIDES. WO 2017189386 A1