Theodrenaline是一种强心剂,也常与cafedrine按比例混合,形成Akrinor,具有降血压的作用。
CAS:13460-98-5
分子式:C17H21N5O5
分子量:375.38
纯度:98%
存储:Store at -20°C
Background:
Theodrenaline is a cardiac stimulant, also acts as an anti-hypotensive agent together with cafedrine.
Akrinor evokes a positive inotropic effect in human atrial trabeculae via stimulation of β-adrenoceptors (AR)[1].
AkrinorTM produces significant potentiation of FSK effects, conceivable by PDE-inhibition, only at very high, clinically irrelevant concentrations of 420 mg/L[1].
[1]. Kloth B, et al. AkrinorTM, a Cafedrine/ Theodrenaline Mixture (20:1), Increases Force of Contraction of Human Atrial Myocardium But Does Not Constrict Internal Mammary Artery In Vitro. Front Pharmacol. 2017 May 23;8:272.