LM-1484是CysLT1受体的拮抗剂,对3H-LTC4位点具有很高的亲和性。
CAS:197506-02-8
分子式:C28H24N4O3
分子量:464.52
纯度:98%
存储:Store at -20°C
Background:
LM-1484 is an antagonist of CysLT1 receptor and displays a higher affinity for 3H-LTC4 sites.
LM-1484 (10 μM) induces the dissociation of 3H-LTD4, and is able to displace 3H-LTC4 from its binding sites[1].
[1]. Ravasi S, et al. Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma. Biochem Pharmacol. 2002 Apr 15;63(8):1537-46.