Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a.
CAS:71828-14-3
分子式:C34H48O8
分子量:584.7
纯度:98%
存储:Store at -20°C
Background:
Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a . It hyperpolarizes P. crassipes muscle fibers with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a aglycone decreases survival of C. elegans (MAC = 0.1 μM). In vivo, avermectin B1a aglycone prevents seizures induced by pentylenetetrazole in mice (ED50 = 43.9 mg/kg) without inducing deficits in rotarod performance.