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4-(2,2,3-Trimethylcyclopentyl)butanoic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4-(2,2,3-Trimethylcyclopentyl)butanoic Acid图片
CAS NO:957136-80-0
规格:98%
分子量:198.3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
4-(2,2,3-Trimethylcyclopentyl)butanoic acid is an orthosteric, insurmountable antagonist of the human bitter taste receptors hTAS2R31 and hTAS2R43.
CAS:957136-80-0
分子式:C12H22O2
分子量:198.3
纯度:98%
存储:Store at -20°C

Background:

4-(2,2,3-Trimethylcyclopentyl)butanoic acid is an orthosteric, insurmountable antagonist of the human bitter taste receptors hTAS2R31 and hTAS2R43. It prevents the activation of hTAS2R31 by saccharin and acesulfame K in cells with IC50 values of 7.9 and 2.4 µM, respectively. In human sensory trials, 4-(2,2,3-trimethylcyclopentyl)butanoic acid significantly reduced the bitter flavor associated with these two artificial sweeteners.