7-keto-25-hydroxy Cholesterol is an oxysterol and a proposed metabolite of 7-keto cholesterol and 7-dehydro cholesterol.
CAS:64907-23-9
分子式:C27H44O3
分子量:416.6
纯度:98%
存储:Store at -20°C
Background:
7-keto-25-hydroxy Cholesterol is an oxysterol and a proposed metabolite of 7-keto cholesterol and 7-dehydro cholesterol . It binds to and activates Smoothened (Smo) at the conserved extracellular cysteine-rich domain (CRD) in a reporter assay. It also increases EGF high affinity binding site numbers in normal rat kidney (NRK) cells.