IDO-IN-5(NLG-1489)是一种哚胺-2,3-双加氧酶(IDO)抑制剂,IC50值为1-10μM,详细信息请参考专利文献WO2012142237A1中的化合物1489。
CAS:1402837-79-9
分子式:C18H21FN2O2
分子量:316.37
纯度:98%
存储:Store at -20°C
Background:
IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM.
IDO-IN-5 (Compound 1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 1-10 μM (this is the concentration of IDO-IN-5 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].
[1]. Mario Mautino, et al. Fused imidazole derivatives useful as ido inhibitors. WO 2012142237 A1.