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Becampanel(AMP 397)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Becampanel(AMP 397)图片
CAS NO:188696-80-2
规格:98%
分子量:330.19
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Becampanel(AMP397)是有效的AMPA拮抗剂,也是一种抗癫痫药。
CAS:188696-80-2
分子式:C10H11N4O7P
分子量:330.19
纯度:98%
存储:Store at -20°C

Background:

Becampanel (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent.


Becampanel is negative in a mouse lymphoma tk assay, which includes a 24 h treatment without S9. A weak micronucleus induction in vitro is found at the highest concentrations tested in V79 cells with S9[1].


Becampanel is negative in the following in vivo studies, which includes the maximum tolerated doses of 320 mg/kg in mice and 2000 mg/kg in rats. Becampanel has no genotoxic potential in vivo[1].


[1]. Suter W, et al. Genotoxicity assessment of the antiepileptic drug AMP397, an Ames-positive aromatic nitro compound. Mutat Res. 2002 Jul 25;518(2):181-94.