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Gastrofensin AN 5 free base
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Gastrofensin AN 5 free base图片
CAS NO:89845-16-9
规格:98%
分子量:344.84
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
GastrofensinAN5freebase是一种4-苯基四氢异喹啉衍生物,是一种抗溃疡剂。
CAS:89845-16-9
分子式:C19H21ClN2O2
分子量:344.84
纯度:98%
存储:Store at -20°C

Background:

Gastrofensin AN 5 free base, a 4-phenyl-tetrahydroisoquinoline derivative, is an antiulcer agent.



Gastrofensin AN 5 supresses the formation of ulcers in all experimental models. From the broad pharmacological studies of Gastrofensin AN 5 on this model it can be seen that even a dose of 0.100 mg/kg has a high antiulcer activity. The increase of the dose leads to a regular increase of the antiulcer activity, the highest suppression of the ulcer index being reaches at a dose of 1 mg/kg (86.15%). The comparative studies with Ranitidine and Cimetidine on the same experimental models of gastric ulcers show that Gastrofensin AN 5 possesses an antiulcer activity many times higher than that of the above-mentioned drugs[1].


[1]. Ivanova N, et al. A new class of antiulcer drugs. I. Antiulcer effect of AN5, a 4-phenyl-tetrahydroisoquinoline derivative, on different experimental models of ulcer in rats. Methods Find Exp Clin Pharmacol. 1990 Jul-Aug;12(6):401-10.