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Indacrinone(MK196)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Indacrinone(MK196)图片
CAS NO:56049-88-8
规格:98%
分子量:365.21
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Indacrinone(MK196)是一种研究性利尿剂,其在大鼠和狗中具有显着的盐水活性,并且在黑猩猩中具有尿酸和盐水活性。
CAS:56049-88-8
分子式:C18H14Cl2O4
分子量:365.21
纯度:98%
存储:Store at -20°C

Background:

Indacrinone (MK196) is an investigational diuretic which has pronounced saluretic activity in the rat and dog as well as both uricosuric and saluretic activity in the chimpanzee.



As the dose increasing from 1 to 10 mg/kg, the amount excreted via the urine decreased from 20 to 11% of administered dose. The amount excretes via the feces is 2-fold higher at the lower dose. At the 10 mg/kg dose the Indacrinone (MK-196)/1 ratio is 0.8 and 5 for the urine and feces, respectively. The urinary ratio of Indacrinone/1 decrease as dose increasing from 10 mg/kg (0.5) to 20 mg/kg (0.2)[1].


[1]. A.G. ZACCHEI, et al. THE PHYSIOLOGICAL DISPOSITION