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Rimeporide(EMD-87580)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rimeporide(EMD-87580)图片
CAS NO:187870-78-6
规格:98%
分子量:333.38
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Rimeporide(EMD-87580)是一种有效的选择性Na+/H+交换泵(NHE-1)抑制剂。
CAS:187870-78-6
分子式:C11H15N3O5S2
分子量:333.38
纯度:98%
存储:Store at -20°C

Background:

Rimeporide (EMD-87580) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).


Blocking NHE-1 activity has been shown to decrease intracellular Na+ and Ca2+ overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1].



[1]. F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.