您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > PH-002
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
PH-002
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PH-002图片
CAS NO:1311174-68-1
规格:98%
分子量:491.58
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
PH-002是一种抑制载脂蛋白(apo)E4神经内分子相互作用的抑制剂,其IC50(FRET)值为116nM。
CAS:1311174-68-1
分子式:C27H33N5O4
分子量:491.58
纯度:98%
存储:Store at -20°C

Background:

PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells that could rescue impairments of mitochondrial motility and neurite outgrowth.


PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells, with an IC50 of 116 nM in FRET[1].


PH-002 is also shown to increase COX1 levels in primary neurons from NSE-apoE4 transgenic mouse cortex and hippocampus. After 4 days of treatment with PH-002 (200 nM), COX1 levels are increased by