PF-05241328是有效的、人电压依赖性钠通道(Nav1.7)的选择性抑制剂，其IC50值为31nM。
CAS：1387633-03-5
分子式：C19H21ClN4O4S
分子量：436.91
纯度：98%
存储：Store at -20°C

Background:

PF-05241328 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (Nav1.7), with an IC50 of 31 nM.

[1]. Jones HM, et al. Clinical Micro-Dose Studies to Explore the Human Pharmacokinetics of Four Selective Inhibitors of Human Nav1.7 Voltage-Dependent Sodium Channels. Clin Pharmacokinet. 2016 Jul;55(7):875-887.