MDL-101146, (S)- is a potent orally bioavailable inhibitor of human neutrophil elastase. References: Durham SL, Hare CM, Angelastro MR, Burkhart JP, Koehl JR, Marquart AL, Mehdi S, Peet NP, Janusz MJ. Pharmacology of N-[4-(4-morpholinylcarbonyl)benzoyl]-L-valyl-N- [3,3,4,4,4-pentafluoro-1-(1-methylethyl)-2-oxobutyl]-L-prolinamide (MDL 101,146): a potent orally active inhibitor of human neutrophil elastase. J Pharmacol Exp Ther. 1994 Jul;270(1):185-91. Erratum in: J Pharmacol Exp Ther 1994 Dec;271(3):1720. PubMed PMID: 8035315.
纯度:≥98%
CAS:163660-59-1