Andrastin A is a meroterpenoid farnesyltransferase inhibitor.
CAS：174232-42-9
分子式：C28H38O7
分子量：486.6
纯度：98%
存储：Store at -20°C

Background:

Andrastin A is a meroterpenoid farnesyltransferase inhibitor. It increases the accumulation and effect of the chemotheraputic agent vincristine (sulfate) , most likely by binding to plasma membrane phosphoglycoprotein to prevent drug efflux. Andrastin A inhibits survival of Caco-2 cells with an IC50 of >50 μg/ml.