Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC50 =<25 nm in a fret activity assay).
CAS：1418274-28-8
分子式：C28H22Cl3N3O5
分子量：586.9
纯度：98%
存储：Store at -20°C

Background:

Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC50 =<25 nm in a fret activity assay). it has fxr agonist mammalian one hybrid (m1h) assay (ec50 =>100 nM).