CAS NO: | 1418741-86-2 |
规格: | 98% |
分子量: | 466.66 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Background:
UNC1079 is the piperidine analog of UNC1021, as a structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies. Target: L3MBTL3The low anticipated affinity of UNC1079 was confirmed, as it demonstrated an activity versus L3MBTL3 of >10 uM by AlphaScreen, which is >1000-fold weaker than UNC1215. UNC1079 also displays weak binding by ITC.
参考文献:
[1]. James LI, et al. Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol. 2013 Mar;9(3):184-91.