BMS-363131 is very potent inhibitor of human tryptase with high selectivity versus other serine proteases, including trypsin. References: Bisacchi GS, Slusarchyk WA, Bolton SA, Hartl KS, Jacobs G, Mathur A, Meng W, Ogletree ML, Pi Z, Sutton JC, Treuner U, Zahler R, Zhao G, Seiler SM. Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase. Bioorg Med Chem Lett. 2004 May 3;14(9):2227-31. PubMed PMID: 15081014.
纯度:≥98%
CAS:384829-65-6