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CAY10649
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAY10649图片
CAS NO:1272519-89-7
规格:98%
分子量:329.8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
5-Lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction.
CAS:1272519-89-7
分子式:C17H12ClNO2S
分子量:329.8
纯度:98%
存储:Store at -20°C

Background:

5-Lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction. CAY10649 is a thiazolinone compound that demonstrates direct inhibition of 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) (IC50 = 0.28 μM) and a soluble fraction of a S100 PMNL cell lysate (IC50 = 0.09 μM) after stimulation with calcium and arachidonic acid.