reacts with nitric oxide to form carboxy-PTI derivatives which in turn inhibits nitric oxide synthase
CAS：148819-94-7
分子式：C14H16KN2O4
分子量：315.38
纯度：98%
存储：Store at -20°C

Background:

Carboxy-PTIO，是一种常用的一氧化氮清除剂，可以用于抑制一氧化氮信号通路。本Carboxy-PTIO为钾盐(Carboxy-PTIO ， potassium salt)。carboxy-PTIO 可以和NO反应生成carboxy-PTI衍生物，同时产生亚硝酸盐或硝酸盐，从而起到清除NO 的作用。

Carboxy-PTIO水溶性很好，溶解度大于20 mg/ml，可溶于一些常见缓冲液如PBS等，也可溶于无水乙醇、甲醇、DMSO、二 甲基甲酰胺。

Carboxy-PTIO常见使用浓度为0.1-10mM。实际的最佳工作浓度请参考相关文献，或根据实验目的，以及所培养的特定细胞 和组织，通过实验进行摸索和优化。

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