Mexiletine(hydrochloride)(KOE-1173(hydrochloride))是钠离子通道阻断剂，ClassIB类抗心律失常化合物。
CAS：5370-01-4
分子式：C11H18ClNO
分子量：215.72
纯度：98%
存储：Store at -20°C

Background:

Mexiletine (hydrochloride) (KOE-1173 (hydrochloride)) is a non-selective voltage-gated sodium channel blocker; Class IB anti-arrhythmic compound.

[1]. Desaphy JF, et al. Effect of mexiletine on sea anemone toxin-induced non-inactivating sodium channels of rat skeletal muscle: a model of sodium channel myotonia. Neuromuscul Disord. 1999 May;9(3):182-9. [2]. Mori K, et al. Inhibitory effects of class I and IV antiarrhythmic drugs on the Na+-activated K+ channel current in guinea pig ventricular cells. Naunyn Schmiedebergs Arch Pharmacol. 1998 Dec;358(6):641-8.